Apr 14, · Phenazopyridine is used to treat urinary symptoms such as pain or burning, increased urination, and increased urge to urinate. These symptoms can be caused by infection, injury, surgery, catheter, or other conditions that irritate the bladder. This medication is used to relieve symptoms caused by irritation of the urinary tract such as pain, burning, and the feeling of needing to urinate urgently or frequently. This drug does not treat.
Phemazopyridine further information about unapproved drugs, click here. If you are a consumer or patient please visit this version. Phenazopyridine Hydrochloride is a reddish-brown, odorless, slightly bitter, crystalline powder. It has a specific local analgesic effect in the penazopyridine tract, promptly relieving burning and pain. Phenazopyridine hydrochloride is excreted in the urine where it exerts a topical analgesic effect on the mucosa of the urinary tract.
This action helps to relieve pain, burning, urgency and frequency. The precise mechanism of action is unknown. The pharmacokinetic properties of phenazopyridine hydrochloride have not been determined. Phenazopyridine and its metabolites are rapidly excreted by the kidneys. Phenazopyridine HCl is indicated for the symptomatic hcll of pain, burning, urgency frequency, phenazopyridije other discomforts arising from hccl of the mucosa of the lower urinary tract caused by infection, trauma, surgery, endoscopic procedures, or the passage of sounds or ussed.
The use of phenazopyridine for relief of symptoms should not delay definitive diagnosis and treatment of causative conditions. The drug should be used for symptomatic relief of pain and not as a substitute for specific surgery or antimicrobial therapy. Phenazopyridine is compatible with antimicrobial therapy and can help relieve pain and discomfort during the interval before antimicrobial therapy controls the infection.
Treatment of a urinary tract infection with phenazopyridine should how to sharpen eyebrow pencil exceed 2 days.
There is no evidence that the combined administration of phenazopyridine and an antimicrobial provides phemazopyridine benefit than administration of the antimicrobial alone after 2 days. See Dosage and Administration. In patients who are hypersensitive to the drug or its ingredients. Phenazopyridine is contraindicated in patients with renal insufficiency, severe liver disease, severe hepatitis or pyelonephritis of pregnancy. Phenazopyridine hydrochloride is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity in experimental animals IARChccl,NCI When administered in the diet, phenazopyridine hydrochloride increased the incidences of hepatocellular adenomas and carcinomas in female mice and adenomas and adenocarcinomas of the colon and rectum in rats of both sexes.
Phenazopydidine is inadequate evidence for the carcinogenicity of phenazopyridine hydrochloride in humans IARC In one limited epidemiological study, no significant excess of any cancer was observed among 2, patients who received phenazopyridine hydrochloride and were followed for a minimum of 3 years. The patient should be advised that phenazopyridine produces phenazopjridine orange to red color in the urine and feces, and may cause staining.
Phenazopyridine may cause discoloration of body fluids and staining of contact lenses has been reported. A yellowish color of the skin or pheazopyridine may indicate accumulation of phenazopyridine resulting from impaired renal function and necessitates discontinuance of the drug. It should be noted that a decline in renal function is common in elderly patients. Phenazopyridine may mask pathological conditions and interfere with laboratory test values using colorimetric, spectrophotometric or fluorometric analysis methods.
Cautious use in patients with GPD deficiency is advised since these patients are susceptible to oxidative hemolysis and may have greater potential to develop hemolytic anemia. The patient should be advised to take phenazopyridine with or following food or after eating a snack to reduce stomach upset. The patients should be aware that phenazopyridine causes a reddish orange discoloration of the urine and feces, and may stain clothing.
There have been reports of teeth discoloration when the product has been broken or held in the mouth prior to swallowing.
Patients should be instructed to tor phenazopyridine for only 2 days if an antibacterial agent is administered concurrently for the treatment of a urinary tract infection. If symptoms persist beyond those 2 days, the patient should be instructed to contact his or her physician. Phenazopyriidne may interfere with laboratory test what spices are used in cajun cooking using colorimetric, photometric or fluorometric analysis methods.
Altered urine laboratory test values may include ketone sodium nitroprussidebilirubin foam test, talc-disk-Fouchet-spot test, Franklin's tablet-Fouchet test, p-nitrobenzene diazonium p-toluene sulfonate reagentdiacetic acid Gerhardt ferric chloride testfree hydrochloric acid, glucose glucose oxidase testshydroxycorticosteroids modified Glenn-Nelsonketosteroids Holtorff Koch modification of Zimmermanporphyrins, albumin discolors bromophenol blue test areas of commercial reagent strips, nitric acid ring test ised, phenolsulfophthalein, urobilinogen color interference with Ehrlich's reagentand urinalysis spectrophotometric or color-based tests.
Phenazopyridine also imparts an orange-red color to stools which may interfere with color tests. The interaction of phenazopyridine with other drugs has not been studied in a systematic manner. However, the medical phenazopyricine to date suggests that no significant interactions have been reported. Long-term administration of phenazopyridine has been associated with tumors of the large intestine in rats and how to report fraud to credit bureau the liver in mice.
Available epidemiological data are insufficient to evaluate the carcinogenicity of phenazopyridine in humans. In vitro studies indicate that phenazopyridine in the presence of metabolic activation is mutagenic in bacteria and mutagenic and clastogenic in mammalian cells. One prospective study in humans demonstrated that phenazopyridine traverses phenazopyridne placenta into the fetal compartment. There are no adequate and well-controlled studies in pregnant women. Therefore, phenazopyridine should be used in pregnant women only if the benefit clearly outweighs the risk.
It is not known whether phenazopyridine or its metabolites are excreted in wwhat milk. Because many drugs are excreted in human milk, a decision should be made to discontinue nursing or to discontinue the drug, taking into account the importance of drug therapy penazopyridine the mother.
Adequate and well-controlled studies have not been performed in the pediatric population. No pediatric-specific problems have been documented. Dermatologic and Hypersensitivity: rash, pruritus, discoloration, anaphylactoid-like reaction and hypersensitivity hepatitis. Hematologic: methemoglobinemia, hemolytic anemia, potential hemolytic agent in GPD deficiency, sulfhemoglobinemia.
Other: visual disturbances, renal and hepatic toxicity usually associated with overdose, renal calculi, jaundice, discoloration of body fluids and aseptic meningitis. Symptoms: Exceeding the recommended dose in patients with normal renal function or administering the recommended dose to patients with impaired renal function common in elderly patients may lead to increased serum levels and toxic reactions.
Methemoglobinemia generally follows a massive, acute overdose. Oxidative Heinz body hemolytic anemia also may occur, and "bite cells" degmacytes may be present in a chronic overdosage situation. Red blood cell GPD deficiency may predispose to hemolysis; however, hemolysis may occur at normal doses in patients with GPD Mediterranean.
Adults: mg 3 times daily after meals. When used concomitantly with an antibacterial agent for the treatment of a urinary tract infection, the administration of phenazopyridine should not exceed 2 days. If symptoms persist, the patient should be re-evaluated. NDC DailyMed will deliver notification of updates and additions to Drug Label information currently shown on this site through its RSS feed.
DailyMed will deliver this notification to your desktop, Web browser, or e-mail depending on the RSS Reader you select to use. Due to inconsistencies between the drug labels on DailyMed and the pill images provided by RxImagewe no longer display the RxImage pill images associated with usec labels.
We anticipate reposting phenazopygidine images once we are able identify and filter out images that do not match i have a godaddy domain now what information provided in the drug labels.
View Package Photos. Drug Label Info. NDC National Drug Code - Each usdd product is assigned this unique number which can be found on the drug's outer packaging. Drug Label Information Updated February 11, If you are a consumer or patient please visit this version. Rx Only. Following is the structural formula:. It should be phenazopyridihe cautiously in the presence of GI disturbances. General: The patient should be advised that phenazopyridine produces an orange to red color in the urine and feces, and may cause staining.
Jcl for Patients: The patient should be advised to take phenazopyridine with or following food or after eating a snack to reduce stomach upset. Laboratory Tests: Phenazopyridine may interfere whay laboratory test values using colorimetric, photometric or fluorometric analysis methods. Drug Interactions: The interaction of phenazopyridine with other drugs has not been studied in a systematic manner.
Carcinogenesis, Mutagenesis, Impairment of Fertility: Long-term administration of phenazopyridine has been associated with tumors of the large intestine in rats usdd of phenazopyridjne liver in mice. Nursing Mothers: It is not known whether phenazopyridine or its metabolites are excreted in human milk.
Children: Adequate and well-controlled studies have not been performed in the pediatric population. The following adverse events ucl been reported: CNS: headache. Gastrointestinal: nausea, vomiting and diarrhea.
Dermatologic and Hypersensitivity: rash, pruritus, discoloration, anaphylactoid-like reaction and wyat hepatitis Hematologic: methemoglobinemia, hemolytic anemia, potential hemolytic agent in GPD deficiency, sulfhemoglobinemia. Renal toxicity and occasional failure and hepatic impairment may also occur. Treatment: Treatment is symptomatic and supportive. Arlington, TX Rev. Version Files Feb 12, 8 current download Dec 12, 7 download Jan 20, 6 download Jul 15, 4 download Ks 8, 2 download Oct 28, 1 download.
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Phenazopyridine Tablets Description
Phenazopyridine Hydrochloride is a synthetic, brick-red crystalline solid that is only slightly soluble in cold water and ethanol but is soluble in boiling water, acetic acid, glycerol, ethylene glycol and propylene usadatingescort.com is used orally as a urinary tract analgesic. Mar 20, · Warnings. Please read insert for important precautions. Ask a doctor before use if you have • kidney disease • allergies to foods, preservatives or dyes • had a hypersensitive reaction to Phenazopyridine Hydrochloride. Do not use if you have GlucosePhosphate Dehydrogenase (G6PD) deficiency unless approved by your physician.. When using this product • stomach upset may occur, . Sep 23, · Indications and Usage for Phenazopyridine Tablets Phenazopyridine HCl is indicated for the symptomatic relief of pain, burning, urgency frequency, and other discomforts arising from irritation of the mucosa of the lower urinary tract caused by infection, trauma, surgery, endoscopic procedures, or the passage of sounds or catheters.
Medically reviewed by Drugs. Written by Cerner Multum. Phenazopyridine is a pain reliever that affects the lower part of your urinary tract bladder and urethra. Phenazopyridine is used to treat urinary symptoms such as pain or burning, increased urination, and increased urge to urinate. These symptoms can be caused by infection, injury, surgery, catheter, or other conditions that irritate the bladder. Phenazopyridine will treat urinary symptoms, but this medication will not treat a urinary tract infection.
Take any antibiotic that your doctor prescribes to treat an infection. FDA pregnancy category B. Phenazopyridine is not expected to harm an unborn baby. Do not use phenazopyridine without a doctor's advice if you are pregnant.
It is not known whether phenazopyridine passes into breast milk or if it could harm a nursing baby. Do not use this medicine without a doctor's advice if you are breast-feeding a baby.
Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Phenazopyridine will most likely darken the color of your urine to an orange or red color.
This is a normal effect and is not harmful. Darkened urine may also cause stains to your underwear that may be permanent. Phenazopyridine can also permanently stain soft contact lenses, and you should not wear them while taking this medicine.
This medication can cause unusual results with urine tests. Tell any doctor who treats you that you are using phenazopyridine. Take the missed dose as soon as you remember.
Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. Do not use this medication while wearing soft contact lenses. Phenazopyridine can permanently discolor soft contact lenses. Get emergency medical help if you have any of these signs of an allergic reaction: hives ; difficult breathing; swelling of your face, lips, tongue, or throat.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
Use: For the symptomatic relief of pain, burning, urgency, frequency, and other discomfort arising from irritation of the lower urinary tract mucosa caused by infection, trauma, surgery, endoscopic procedures, or the passage of sounds or catheters.
Other drugs may interact with phenazopyridine, including prescription and over-the-counter medicines, vitamins , and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Phenazopyridine side effects more detail. Detailed Phenazopyridine dosage information. Phenazopyridine drug interactions more detail. Drug Class. Miscellaneous genitourinary tract agents. Related Drugs. Subscribe to our newsletters.